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Branching morphogenesis over two days by Madin-Darby canine kidney cells in response to hepatocyte growth factor (HGF). Images were acquired by fluorescence confocal microscopy, showing the structural protein actin, which highlights cell borders. Left: multicellular hollow spheres of cells, termed acini, were grown in 3D culture.
A Korean study estimated a disease-specific overall five-year survival rate of 85%. [109] Taken as a whole, if the disease is limited to the kidney, only 20–30% develop metastatic disease after nephrectomy. [110] More specific subsets show a five-year survival rate of around 90–95% for tumors less than 4 cm. For larger tumors confined to ...
The incidence rate of CKD in dogs was 15.8 cases per 10,000 dog years at risk. The mortality rate of CKD was 9.7 deaths per 10,000 dog years at risk. (Rates developed from a population of 600,000 insured Swedish dogs; one dog year at risk is one dog at risk for one year). The breeds with the highest rates were the Bernese mountain dog ...
[3] [4] [5] The typical canine diabetes patient is middle-aged, female, and overweight at diagnosis. [6] The number of dogs diagnosed with diabetes mellitus has increased three-fold in thirty years. In survival rates from around the same time, only 50% survived the first 60 days after diagnosis and went on to be successfully treated at home.
Erythrocyte fragility refers to the propensity of erythrocytes (red blood cells, RBC) to hemolyse (rupture) under stress. It can be thought of as the degree or proportion of hemolysis that occurs when a sample of red blood cells are subjected to stress (typically physical stress, and most commonly osmotic and/or mechanical stress).
It is not essential for a female dog to either experience a heat cycle or have puppies before spaying, and likewise, a male dog does not need the experience of mating before neutering. Female cats and dogs are seven times more likely to develop mammary tumors if they are not spayed before their first heat cycle. [77]
Alabama rot, Greenetrack disease, or cutaneous and renal glomerular vasculopathy (CRGV) [1] is an often fatal condition in dogs. It was first identified in the US in the 1980s in greyhounds. [2] [3] The high number of affected dogs at the Greenetrack Racing Park, Alabama, led to the initial pseudonyms of Greenetrack Disease and Alabama Rot. [4]
Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]