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Evidence of decline in lung function as measured by pulmonary function testing can occur as quickly as 24 hours of continuous exposure to 100% oxygen, [42] with evidence of diffuse alveolar damage and the onset of acute respiratory distress syndrome usually occurring after 48 hours on 100% oxygen. [41] Breathing 100% oxygen also eventually ...
Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.
High altitude breathing apparatus is used for unpressurised (ambient pressure) aeronautical and mountaineering activities where the oxygen content of the natural atmosphere is insufficient for maintaining physical activity, consciousness, or life, but the atmospheric pressure is sufficient that a pressure suit is not needed.
The bag-valve-mask device has a self-inflating bag with a soft mask that rests on the face. When the bag is connected to an oxygen supply, the patient will receive 60 to 100% of inspired oxygen. The purpose of bag-valve-mask is to provide adequate temporary ventilation and allow the body to achieve airway control by itself.
Above 12,000 metres (40,000 ft), positive pressure breathing with 100% oxygen is essential, as without positive pressure even very short exposures to altitudes above 13,000 metres (43,000 ft) lead to loss of consciousness. [57]
This can be caused by breathing air at a pressure above normal or by breathing other gas mixtures with a high oxygen fraction, high ambient pressure or both. The body is tolerant of some deviation from normal inspired oxygen partial pressure, but a sufficiently elevated level of hyperoxia can lead to oxygen toxicity over time, with the ...
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