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Orthology may refer to: . Orthology (biology) - homologous sequences originate from the same ancestors (homolog e.g. all globin protein), which are separated from each other after a speciation event, e.g. human beta and chimp beta globin.
The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [5] For instance, the plant Flu regulatory protein is present both in Arabidopsis (multicellular higher plant) and Chlamydomonas (single cell green algae).
The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [41] Homologous sequences are paralogous if they were created by a duplication event within the genome. For gene duplication events, if a gene in an organism is duplicated, the two copies are paralogous. They can shape the structure of whole genomes and thus ...
6469 20423 Ensembl ENSG00000164690 ENSMUSG00000002633 UniProt Q15465 Q62226 RefSeq (mRNA) NM_000193 NM_001310462 NM_009170 RefSeq (protein) NP_000184 NP_001297391 NP_033196 Location (UCSC) Chr 7: 155.8 – 155.81 Mb Chr 5: 28.66 – 28.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sonic hedgehog protein (SHH) is encoded for by the SHH gene. The protein is named after the video ...
DAF-16 is the sole ortholog of the FOXO family of transcription factors in the nematode Caenorhabditis elegans. [1] It is responsible for activating genes involved in longevity, lipogenesis, heat shock survival and oxidative stress responses.
Orthology is the study of linguistic norms. The word comes from Greek ortho- ("correct") and -logy ("science of"). This science is a place where psychology, philosophy, linguistics and other fields of learning come together.
Syntelog: a special case of gene homology where sets of genes are derived from the same ancestral genomic region. This may arise from speciation events, or through whole or partial genome duplication events (e.g. polyploidy).
Orthology is defined relative to the last common ancestor of the species being considered, thereby determining the hierarchical nature of orthologous classifications.