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The subcategorization of Letterer-Siwe disease is a historical eponym. [2] Designating the four subtypes of LCH as separate entities are mostly of historical significance, because they are varied manifestations of the same underlying disease process, and patients also often exhibit symptoms from more than one of the four syndromes. [1]
The disease has gone by several names, including Hand–Schüller–Christian disease, Abt-Letterer-Siwe disease, Hashimoto-Pritzker disease (a very rare self-limiting variant seen at birth) and histiocytosis X, until it was renamed in 1985 by the Histiocyte Society.
[8] [21] Shortly afterwards, Letterer in 1924 and Siwe in 1933 described a fatal condition in children who presented with large livers and spleens, large lymph nodes and bone damage. In 1940, Louis Litchtenstein and Henry L. Jaffe described a self-limiting disease characterised by "isolated bone lesions". [ 9 ]
Doctor reviewing a radiation treatment plan. In radiotherapy, radiation treatment planning (RTP) is the process in which a team consisting of radiation oncologists, radiation therapist, medical physicists and medical dosimetrists plan the appropriate external beam radiotherapy or internal brachytherapy treatment technique for a patient with cancer.
In a randomized trial (i.e., an experimental study), the average treatment effect can be estimated from a sample using a comparison in mean outcomes for treated and untreated units. However, the ATE is generally understood as a causal parameter (i.e., an estimate or property of a population ) that a researcher desires to know, defined without ...
Pathology – study of causes and pathogenesis of diseases. Pediatrics – branch of medicine that deals with the general health and well-being of children and in some countries like the U.S. young adults. Preventive medicine – measures taken for disease prevention, as opposed to disease treatment.
Sture Siwe (1897–1966), Swedish pediatrician who described Letterer–Siwe disease; Alphonse Siyam Siwe (born 1953), Cameroonian politician; Lisa Siwe (born 1968), Swedish director; Tom Siwe (born 1987), Swedish footballer; Jacques Siwe (born 2001), French footballer
recognition and treatment by the folk medicine of the culture; Some culture-specific syndromes involve somatic symptoms (pain or disturbed function of a body part), while others are purely behavioral. Some culture-bound syndromes appear with similar features in several cultures, but with locally specific traits, such as penis panics.