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Amoebiasis, or amoebic dysentery, is an infection of the intestines caused by a parasitic amoeba Entamoeba histolytica. [3] [4] Amoebiasis can be present with no, mild, or severe symptoms. [2] Symptoms may include lethargy, loss of weight, colonic ulcerations, abdominal pain, diarrhea, or bloody diarrhea.
Poor sanitary conditions are known to increase the risk of contracting amebiasis E. histolytica. [11] In the United States, there is a much higher rate of amebiasis-related mortality in California and Texas (this might be caused by the proximity of those states to E. histolytica-endemic areas, such as Mexico), parts of Latin America, and Asia. [12]
Balamuthia mandrillaris can also cause cutaneous amoebiasis, but can prove fatal if the amoeba enters the bloodstream [7] [8] It is characterized by ulcers. Diagnosis of amebiasis cutis calls for high degree of clinical suspicion. This needs to be backed with demonstration of trophozoites from lesions. Unless an early diagnosis can be made such ...
Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. [3] It is a first-line treatment for amebiasis or giardiasis during pregnancy. [3] Otherwise, it is generally a second line treatment option. [3]
Diloxanide furoate works only in the digestive tract and is a lumenal amebicide. [2] [6] It is considered second line treatment for infection with amoebas when no symptoms are present but the person is passing cysts, in places where infections are not common.
Treatment by use of primitive medicines [ edit ] The Nicobarese people have attested to the medicinal properties found in Glochidion calocarpum , a plant endemic to India, saying that its bark and seed are most effective in curing abdominal disorders associated with amoebiasis .
The usage of conventional therapeutics to treat amoebiasis if often linked with substantial side effects, a threat to the efficacy of these therapeutics, further worsened by the development of drug resistance in the parasite. [20] Amoebic meningoencephalitis and keratitis is a brain-eating amoeba caused by free-living Naeglaria and Acanthomoeba.
Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. [ 1 ] [ 2 ] [ 3 ] It was available for amebiasis in the United States as late as 1991.