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Citicoline , also known as cytidine diphosphate-choline (CDP-choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.
alkylacylglycerol choline phosphotransferase, alkylacylglycerol cholinephosphotransferase, CDP-choline diglyceride phosphotransferase, cholinephosphotransferase, CPT, cytidine diphosphocholine glyceride transferase, cytidine diphosphorylcholine diglyceride transferase, diacylglycerol choline phosphotransferase, phosphocholine ...
Choline-phosphate cytidylyltransferase (EC 2.7.7.15) is an enzyme that catalyzes the chemical reaction CTP + choline phosphate ⇌ {\displaystyle \rightleftharpoons } diphosphate + CDP-choline where the two substrates of this enzyme are CTP and choline phosphate , and the two products are diphosphate and CDP-choline .
De novo synthesis of phosphatidylcholine in the lung arises primarily from cytidine diphosphate-choline (CDP-choline). The transformation of CDP-choline to phosphatidylcholine is effected by choline phosphate cytidyltransferase. Under certain conditions the enzymes choline kinase, glycerol-3-phosphate acyltransferase and phosphatidate ...
Cytidine diphosphate, abbreviated CDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside cytidine. CDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase cytosine. In Bacillus subtilis and Staphylococcus aureus, CDP-activated glycerol and ribitol are necessary to build wall ...
CDP-diacylglycerol + choline CMP + phosphatidylcholine Thus, the two substrates of this enzyme are CDP-diacylglycerol and choline , whereas its two products are CMP and phosphatidylcholine . This enzyme belongs to the family of transferases , specifically those transferring non-standard substituted phosphate groups.
Phosphatidylglycerol (PG) is formed via a complex sequential pathway whereby phosphatidic acid (PA) is first converted to CDP-diacylglyceride by the enzyme CDP-diacylglyceride synthase. [2] Then a PGP synthase enzyme exchanges glycerol-3-phosphate (G3P) for cytidine monophosphase (CMP), forming the temporary intermediate ...
The systematic name of this enzyme class is CDP-choline:sphingosine cholinephosphotransferase. Other names in common use include CDP-choline-sphingosine cholinephosphotransferase , phosphorylcholine-sphingosine transferase , cytidine diphosphocholine-sphingosine cholinephosphotransferase , and sphingosine choline phosphotransferase .