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BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.
It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of congenic strains, easy breeding, and robustness. [1] The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 ...
These mice are then infected with the virus and researchers are able to study how HIV attacks the human lymphocytes and causes acquired immunodeficiency syndrome (AIDS) over time. [2] Furthermore, humanized mouse models can also be used to test potential therapies for this disease, including gene-based therapies. [3]
ICR may refer to: Biology. Idiopathic condylar resorption, a temporomandibular joint disorder; Immunological constant of rejection, Immunology concept relating to ...
The albino laboratory mouse is an iconic model organism for scientific research in a variety of fields An SCID Intermediate coat colour Kept as a pet. The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets.
The Immunologic Constant of Rejection (ICR), is a notion introduced by biologists to group a shared set of genes expressed in tissue destructive-pathogenic conditions like cancer and infection, along a diverse set of physiological circumstances of tissue damage or organ failure, including autoimmune disease or allograft rejection. [1]
Abbreviation Meaning 131 I or I131: iodine-131 (aka radioactive iodine or radioiodine) IA: intra-arterial: intra-articular: IAA: insulin autoantibody IABP: intra-aortic balloon pump: IAI: intra-amniotic infection: IBC: inflammatory breast cancer: IBD: inflammatory bowel disease: IBS: irritable bowel syndrome: IC: ileocecal: immunocompromised ...
Establishment of Tg-rasH2 mouse, in which a human prototype c-Ha-ras oncogene is introduced, and evaluation of their practical usefulness. Achieved a high level of accuracy in carcinogenicity testing for drugs and reduced the testing period to six months from the conventional two years' system.