Search results
Results From The WOW.Com Content Network
An anti-α-synuclein drug, or an α-synuclein inhibitor, is a drug which blocks or inhibits α-synuclein. [ 1 ] [ 2 ] α-Synuclein is a protein which is thought to be involved in the development and progression of α-synucleinopathies including Parkinson's disease , dementia with Lewy bodies , and multiple system atrophy .
Alpha-synuclein is a synuclein protein primarily found in neural tissue, making up as much as one percent of all proteins in the cytosol of brain cells. [17] It is expressed highly in neurons within the frontal cortex, hippocampus, striatum, and olfactory bulb, [17] but can also be found in the non-neuronal glial cells. [18]
Mutations in alpha-synuclein are associated with early-onset familial Parkinson's disease and the protein aggregates abnormally in Parkinson's disease, Lewy body disease, and other neurodegenerative diseases. [5] [6] The gamma-synuclein protein's expression in breast tumors is a marker for tumor progression. [7] [8]
If Amazon were to sustain a 10% annualized growth rate in cash flow through 2030 (based on the $18.64-per-share consensus for 2027), its multiple would drop to just 7.
The DNA repair function of alpha-synuclein appears to be compromised in Lewy body inclusion bearing neurons, and this may trigger cell death. Study of synucleinopathy mouse models of Parkinson's disease indicates that alpha-synuclein pathogenesis is associated with increased DNA damage and activation of the DNA damage response. [19]
The stock's 300% run since 2023 has investors thinking big about the future. ... $13 billion in revenue in 2030. Using today's price-to ... a high market cap by 2030 will be challenging. Palantir ...
Nvidia has an incredible CAGR of 93%, while Tesla's is 74% -- all of that growth coming in the years between 2019 and 2022. And there are others that have come close. Eli Lilly 's five-year CAGR ...
Beta-synuclein is a protein that in humans is encoded by the SNCB gene. [ 5 ] [ 6 ] [ 7 ] The protein encoded by this gene is highly homologous to alpha-synuclein .