Search results
Results From The WOW.Com Content Network
The two DNA strands are known as polynucleotides as they are composed of simpler monomeric units called nucleotides. [2] [3] Each nucleotide is composed of one of four nitrogen-containing nucleobases (cytosine [C], guanine [G], adenine [A] or thymine [T]), a sugar called deoxyribose, and a phosphate group.
They are helical in shape and contain guanine tetrads that can form from one, [3] two [4] or four strands. [5] The unimolecular forms often occur naturally near the ends of the chromosomes, better known as the telomeric regions, and in transcriptional regulatory regions of multiple genes, both in microbes [ 6 ] [ 7 ] and across vertebrates [ 8 ...
Secondary structure is the set of interactions between bases, i.e., which parts of strands are bound to each other. In DNA double helix, the two strands of DNA are held together by hydrogen bonds. The nucleotides on one strand base pairs with the nucleotide on the other strand. The secondary structure is responsible for the shape that the ...
In DM1 the DNA sequence that is expanded is CTG while in DM2 it is CCTG. These two sequences are found on different genes with the expanded sequence in DM2 being found on the ZNF9 gene and the expanded sequence in DM1 found on the DMPK gene. The two genes don't encode for proteins unlike other disorders like Huntington's disease or Fragile X ...
The following table is a representative sample of Erwin Chargaff's 1952 data, listing the base composition of DNA from various organisms and support both of Chargaff's rules. [17] An organism such as φX174 with significant variation from A/T and G/C equal to one, is indicative of single stranded DNA.
Nucleic acids consist of a chain of linked units called nucleotides. Each nucleotide consists of three subunits: a phosphate group and a sugar (ribose in the case of RNA, deoxyribose in DNA) make up the backbone of the nucleic acid strand, and attached to the sugar is one of a set of nucleobases.
Each human cell contains around two metres of DNA, which must be tightly folded to fit inside the cell nucleus. However, in order for the cell to function, proteins must be able to access the sequence information contained within the DNA, in spite of its tightly-packed nature. Hence, the cell has a number of mechanisms in place to control how ...
Minisatellite: Short repeats of nucleotides. Microsatellite: Very short repeats of nucleotides. Some trinucleotide repeats are found in coding regions (see, Trinucleotide repeat disorder). Most are found in noncoding regions. Their function is unknown, if they have any specific function. They are used as molecular markers and in DNA fingerprinting.