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Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
In the United States it is a second-line treatment to ceftriaxone for gonorrhea. [5] It is taken by mouth. [5] Common side effects include diarrhea, abdominal pain, and nausea. [5] Serious side effects may include allergic reactions and Clostridioides difficile diarrhea. [5] It is not recommended in people with a history of a severe penicillin ...
Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is contraindicated: Produces toxic free radicals that disrupt DNA and proteins. This non-specific mechanism is responsible for its activity against a variety of bacteria, amoebae, and protozoa ...
Individuals weighing less than 150 kg are typically prescribed a ceftriaxone concentration of 500 mg, while individuals who weigh over 150 kg are typically prescribed a dose of 1 g. Although ceftriaxone is not the only cephalosporin that has been effective at treating gonorrhoeae, it is the most advantageous. [75]
Other bacteria such as non–group A β-hemolytic streptococci and fusobacterium may also cause pharyngitis. [ 13 ] [ 15 ] It is spread by direct, close contact with an infected person; thus crowding, as may be found in the military and schools, increases the rate of transmission.
As of 2016, both ceftriaxone by injection and azithromycin by mouth are most effective. [4] [57] [58] [59] However, due to increasing rates of antibiotic resistance, local susceptibility patterns must be taken into account when deciding on treatment. [36] [60] Ertapenem is a potential effective alternative treatment for ceftriaxone-resistant ...
Bacteria in the biofilm community can actually generate various toxic compounds that interfere with the growth of other competing bacteria. [citation needed] S. mutans has over time developed strategies to successfully colonize and maintain a dominant presence in the oral cavity. The oral biofilm is continuously challenged by changes in the ...
These bacteria commonly inhabit the skin and nose where they are innocuous, but may enter the body through cuts or abrasions which may be nearly invisible. Once inside the body, the bacteria may spread to a number of body systems and organs, including the heart, where the toxins produced by the bacteria may cause cardiac arrest .