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This is a laboratory rat with a brain implant, that was used to record in vivo neuronal activity. Studies that are in vivo (Latin for "within the living"; often not italicized in English [1] [2] [3]) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead ...
It was coined in 1987 as an allusion to the Latin phrases in vivo, in vitro, and in situ, which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature.
Biological systems exist as a complex interplay of countless cellular components interacting across four dimensions to produce the phenomenon called life. While it is common to reduce living organisms to non-living samples to accommodate traditional static imaging tools, the further the sample deviates from the native conditions, the more likely the delicate processes in question will exhibit ...
IVIVE in pharmacology can be used to assess pharmacokinetics (PK) or pharmacodynamics (PD).. [citation needed]Since biological perturbation depends on concentration of the toxicant as well as exposure duration of a candidate drug (parent molecule or metabolites) at that target site, in vivo tissue and organ effects can either be completely different or similar to those observed in vitro.
The in vivo bioreactor is a tissue engineering paradigm that uses bioreactor methodology to grow neotissue in vivo that augments or replaces malfunctioning native tissue. . Tissue engineering principles are used to construct a confined, artificial bioreactor space in vivo that hosts a tissue scaffold and key biomolecules necessary for neotissue
This is an activity-dependent event. Partial blockage of the receptor leads to retraction of corresponding presynaptic terminals. Later they used a connectomic approach, i.e., tracing out all the connections between motor neurons and muscle fibers, to characterize developmental synapse elimination on the level of a full circuit.
Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. [ 3 ] Anatomy is inherently tied to developmental biology , embryology , comparative anatomy , evolutionary biology , and phylogeny , [ 4 ] as these are the processes by which ...
Mice are the most commonly used mammal species for live animal research. Such research is sometimes described as vivisection. Vivisection (from Latin vivus 'alive' and sectio 'cutting') is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure.