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  2. Trimethoprim - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim

    Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. [1] [2] It is taken orally (swallowed by mouth). [1]

  3. Trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

    The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...

  4. Sleep inversion - Wikipedia

    en.wikipedia.org/wiki/Sleep_inversion

    Sleep inversion may be a symptom of elevated blood ammonia levels [2] and is often an early symptom of hepatic encephalopathy. [3] Sleep inversion is a feature of African trypanosomiasis, after which the disease takes its common name, "African sleeping sickness"; [4] sleep-wake cycle disturbances are the most common indication that the disease has reached the stage where infection spreads into ...

  5. List of side effects of trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/List_of_side_effects_of...

    Megaloblastic anaemia; Methaemoglobinaemia; Erythema multiforme; Low blood sugar; Hepatitis (liver swelling); Crystalluria (crystals in the urine); Urinary obstruction causing difficulty passing urine

  6. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    Insufficient quality or quantity of night time sleep [5] Obstructive sleep apnea [6] Misalignments of the body's circadian pacemaker with the environment (e.g., jet lag, shift work, or other circadian rhythm sleep disorders) [7] Another underlying sleep disorder, such as narcolepsy, sleep apnea, [8] idiopathic hypersomnia, or restless legs syndrome

  7. Sleep deprivation - Wikipedia

    en.wikipedia.org/wiki/Sleep_deprivation

    Sleep apnea is a serious disorder that has symptoms of both insomnia and sleep deprivation, among other symptoms like excessive daytime sleepiness, abrupt awakenings, and difficulty concentrating. [131] It is a sleep related breathing disorder that can cause partial or complete obstruction of the upper airways during sleep. [132]