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This is a laboratory rat with a brain implant, that was used to record in vivo neuronal activity. Studies that are in vivo (Latin for "within the living"; often not italicized in English [1] [2] [3]) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead ...
A scientific theory is an explanation of an aspect of the natural world that can be or that has been repeatedly tested and has corroborating evidence in accordance with the scientific method, using accepted protocols of observation, measurement, and evaluation of results.
Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
When a hypothesis has survived a sufficient number of tests, it may be promoted to a scientific theory. A theory is a hypothesis that has survived many tests and seems to be consistent with other established scientific theories. Since a theory is a promoted hypothesis, it is of the same 'logical' species and shares the same logical limitations.
IVIVE in pharmacology can be used to assess pharmacokinetics (PK) or pharmacodynamics (PD).. [citation needed]Since biological perturbation depends on concentration of the toxicant as well as exposure duration of a candidate drug (parent molecule or metabolites) at that target site, in vivo tissue and organ effects can either be completely different or similar to those observed in vitro.
It was coined in 1987 as an allusion to the Latin phrases in vivo, in vitro, and in situ, which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature.
Behavioral neuroscience in relation to systems neuroscience focuses on representational dissimilarity matrices (RDMs), which categorizes brain activity patterns and compares them across different conditions, such as the dissimilar level of brain activity observing an animal in comparison to an inanimate object.
The in vivo bioreactor is a tissue engineering paradigm that uses bioreactor methodology to grow neotissue in vivo that augments or replaces malfunctioning native tissue. . Tissue engineering principles are used to construct a confined, artificial bioreactor space in vivo that hosts a tissue scaffold and key biomolecules necessary for neotissue