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The entourage effect is a hypothesis that cannabis compounds other than tetrahydrocannabinol (THC) act synergistically with it to modulate the overall psychoactive effects of the plant.
Majority of terpenes found in cannabis are hydrocarbons, which are a direct product of terpene synthase (TPS) enzymes. [13] The molecular make up of terpenes in a cannabis plant involves the linking and elongation of chains in hydrocarbons and isoprene units, formed by isopentenyl pyrophosphate and dimethylallyl pyrophosphate.
1,1,6-Trimethyl-1,2-dihydronaphthalene (TDN) is an aroma compound present in wine, [1] particularly aged Rieslings. [ 2 ] [ 3 ] Chemically, it is classified as a 13C-norisoprenoid, as it has thirteen carbon atoms, and is derived from an isoprenoid by the loss of methylene groups.
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
In Phase III trials, the most common adverse effects were dizziness, drowsiness and disorientation; 12% of subjects stopped taking the drug because of the side effects. [ 57 ] Dronabinol (brand names Marinol and Syndros) is a delta-9-THC containing drug for treating HIV/AIDS -induced anorexia and chemotherapy-induced nausea and vomiting .
Terpenes (98) Vitamins (1) Cannabis also produces numerous volatile sulfur compounds that contribute to the plant's skunk-like aroma, with Prenylthiol (3-methyl-2-butene-1-thiol) identified as the primary odorant. [15] These compounds are found in much lower concentrations than the major terpenes and sesquiterpenes.
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By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms triterpene and triterpenoid often are used interchangeably. Triterpenoids possess a rich chemistry and pharmacology (e.g. cholesterol) with several pentacyclic motifs.