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Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
It is necessary for a network of blood vessels to be established as soon as possible to provide the growing tissue with nutrients, to take away cellular wastes, and transport new leukocytes to the area. Fibroblasts, the main cells that deposit granulation tissue, depend on oxygen to proliferate and lay down the new extracellular matrix. [7]
Pyogenic granulomas can grow rapidly and often bleed profusely with little or no trauma. They may exude an oil-like substance, causing the surface to be damp. This is especially true if the granuloma is located on the scalp. [medical citation needed]
A giant cell (also known as a multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. [1] Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles.
Gummas have a firm, necrotic center surrounded by inflamed tissue, which forms an amorphous proteinaceous mass. The center may become partly hyalinized.These central regions begin to die through coagulative necrosis, though they also retain some of the structural characteristics of previously normal tissues, enabling a distinction from the granulomas of tuberculosis where caseous necrosis ...
It may develop rapidly from a periapical granuloma, as a consequence of untreated chronic periapical periodontitis. [ 1 ] Periapical is defined as "the tissues surrounding the apex of the root of a tooth " and a cyst is "a pathological cavity lined by epithelium , having fluid or gaseous content that is not created by the accumulation of pus."
This type of epulis is neither pyogenic ("pus producing") nor a true granuloma, but it is a vascular lesion.About 75% of all pyogenic granulomas occur on the gingiva, [2] growing beneath the gingival margin, [8] although they may also occur elsewhere in the mouth or other parts of the body (where the term epulis is inappropriate).
Umbilical granulomas appear as round, pink lumps found at the base of the umbilicus after the removal of the umbilical cord. It appears small, pink/red, and moist due to cord separation. They are usually 1–10 mm in size, however grow in size if they are not treated. Umbilical granulomas are also painless since they do not contain nerve fibers ...