Search results
Results From The WOW.Com Content Network
Phenylketonuria is an inherited genetic disorder. It is caused by mutations in the PAH gene, which can result in inefficient or nonfunctional phenylalanine hydroxylase, an enzyme responsible for the metabolism of excess phenylalanine. This results in the buildup of dietary phenylalanine to potentially toxic levels.
Peking University. Peking University (PKU) is a public university in Haidian, Beijing, China. It is affiliated with and funded by the Ministry of Education of China. The university is part of the Double First-Class Construction and the C9 League. It was a part of the now-defunct Project 211 and Project 985.
15–75 per 1,000,000 births. [1] Hyperphenylalaninemia is a medical condition characterized by mildly or strongly elevated concentrations of the amino acid phenylalanine in the blood. Phenylketonuria (PKU) can result in severe hyperphenylalaninemia. [2] Phenylalanine concentrations are routinely screened in newborns by the neonatal heel prick ...
However, people who have phenylketonuria (PKU) have to be cautious with how much they're getting. PKU is a rare inherited genetic disorder that affects how the body processes phenylalanine.
245 880.10 g·mol −1. Pegvaliase, sold under the brand name Palynziq, is a medication used for the treatment of the genetic disease phenylketonuria. [5][9][10] It is a phenylalanine (Phe)‑metabolizing enzyme. [5] Chemically, it is a pegylated derivative of the enzyme phenylalanine ammonia-lyase that metabolizes phenylalanine to reduce its ...
Phenylalanine hydroxylase (PAH) (EC 1.14.16.1) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine.PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH 4, a pteridine cofactor) and a non-heme iron for catalysis.
Frequency. ~1 in 135 [ 14 ] Coeliac disease (British English) or celiac disease (American English) is a long-term autoimmune disorder, primarily affecting the small intestine, where individuals develop intolerance to gluten, present in foods such as wheat, rye and barley. [ 10 ] Classic symptoms include gastrointestinal problems such as chronic ...
IPA. [tsʰɪŋ˥ wa˩ taj˨ hɔk̚˨] Tsinghua University is a public university in Haidian, Beijing, China, affiliated with and funded by the Ministry of Education of China. The university is part of Project 211, Project 985, and the Double First-Class Construction. It is also a member of the C9 League.