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Topical steroid withdrawal, also known as red burning skin and steroid dermatitis, has been reported in people who apply topical steroids for 2 weeks or longer and then discontinue use. [ 4 ] [ 5 ] [ 2 ] [ 1 ] Symptoms affect the skin and include redness, a burning sensation, and itchiness, [ 2 ] which may then be followed by peeling.
Steroid-induced skin atrophy is thinning of the skin as a result of prolonged exposure to topical steroids. In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8]
Irritant dermatitis is usually found on hands whereas exposed areas of skin. Symptoms of both forms include the following: Red rash: This is the usual reaction. The rash appears immediately in irritant contact dermatitis; in allergic contact dermatitis, the rash sometimes does not appear until 24–72 hours after exposure to the allergen.
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Cortisone is a pregnene (21-carbon) steroid hormone.It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
[10] [11] Side effects after long-term usage include eyesight damage, elevated blood sugar levels and adrenal gland disorders. [12] Topical hydrocortisone is available in several dosage forms such as solution, lotion, cream, ointment and spray. [19] Some brand names for topical hydrocortisone include Anusol HC, Cortizone 10, and Synacort. [19]
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In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. [1] The area of skin involved can vary from small to covering the entire body. [1] [2] Dermatitis is also called eczema but the same term is often used for the most common type of skin inflammation, atopic dermatitis. [7]