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The fornix (from Latin: fornix, lit. 'arch'; pl.: fornices) is a C-shaped bundle of nerve fibers in the brain that acts as the major output tract of the hippocampus. The fornix also carries some afferent fibers to the hippocampus from structures in the diencephalon and basal forebrain. The fornix is part of the limbic system. While its exact ...
The fornix is a C-shaped bundle of axons that begins in the hippocampal formation of both hemispheres, referred to as the fimbria, and extend through the crus of fornix, also known as the posterior pillars. The fimbria section of the fornix is directly connected to the alveus, which is a portion of the hippocampal formation that arises from the ...
The anterior commissure (also known as the precommissure) is a tract that connects the two temporal lobes of the cerebral hemispheres across the midline, and placed in front of the columns of the fornix.
A major output goes via the fornix to the lateral septal area and to the mammillary body of the hypothalamus (which the fornix interconnects with the hippocampus). [20] The hippocampus receives modulatory input from the serotonin, norepinephrine, and dopamine systems, and from the nucleus reuniens of the thalamus to field CA1.
The subfornical organ (SFO) is one of the circumventricular organs of the brain. [1] [2] Its name comes from its location on the ventral surface of the fornix near the interventricular foramina (foramina of Monro), which interconnect the lateral ventricles and the third ventricle.
A heuristic model of the neural pathway of the Papez circuit shows the connections between its different parts. Based on Papez's experiment with aggression in rats and other studies, it was initially believed that the circuit was involved with emotion. The circuit connects the hypothalamus and the cortex and acts as the emotional system of the ...
Central nucleus (autonomic nervous system) Medial nucleus (accessory olfactory system) Cortical and basomedial nuclei (main olfactory system) Lateral and basolateral nuclei (frontotemporal cortical system) Extended amygdala. Stria terminalis. Bed nucleus of the stria terminalis; Claustrum; Basal ganglia. Striatum. Dorsal striatum (a.k.a ...
In 1937, Papez theorized that a circuit including the hippocampal formation constitutes the neural substrate of emotional behavior, [6] and Klüver and Bucy reported that, in monkeys, surgical removal of the hippocampal formation and the amygdaloid complex has a profound effect on emotional responses.