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The usage expanded to include topical treatment of herpes simplex, [102] zoster, and varicella. [103] Some trials combined different antivirals with differing results. [ 97 ] The introduction of 9-β-D-arabinofuranosyladenine, (ara-A or vidarabine), considerably less toxic than ara-C, in the mid-1970s, heralded the way for the beginning of ...
Aciclovir acts by inhibiting viral DNA replication and is used for the treatment of herpes simplex virus (HSV) and varicella zoster virus infections, including: [3] [15] [16] Genital herpes simplex (treatment and prevention) Neonatal herpes simplex; Herpes simplex labialis ; Shingles; Acute chickenpox in immunocompromised patients
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [ 1 ] When symptoms do occur, they typically include small blisters that break open to form painful ulcers . [ 1 ]
Treatment: “Your dermatologist may freeze them with liquid nitrogen, apply other topical treatments or lasers, or give you a prescription for a cream to use at home," Dr. Zeichner says. Alamy ...
Resiquimod (R-848) is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel [1] in the treatment of skin lesions [2] such as those caused by the herpes simplex virus [3] [4] and cutaneous T cell lymphoma, [5] and as an adjuvant to increase the effectiveness of vaccines. [6]
The drug was approved as a cream for oral herpes after clinical trials by the FDA in July 2000. [4] [14] It was shown to shorten the healing by 17.5 hours on average (95% confidence interval: 2 to 22 hours) in a placebo-controlled trial. [15] Another trial showed no effect when treating the infected backs of guinea pigs. [16]