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Papilledema: "The underlying mechanism for visual obscurations in all of these patients appear to be transient ischemia of the optic nerve head consequent to increased tissue pressure. Axonal swelling, intraneural masses, and increased influx of interstitial fluid may all contribute to increases in tissue pressure in the optic nerve head.
Those who do experience symptoms typically report "transient visual obscurations", episodes of difficulty seeing that occur in both eyes but not necessarily at the same time. Long-term untreated papilledema leads to visual loss, initially in the periphery but progressively towards the center of vision. [5] [9]
The third case of visual changes while on board the ISS had no changes in visual acuity and no complaints of headaches, transient visual obscurations, diplopia or pulsatile tinnitus during the mission. Upon return to Earth, no eye issues were reported by the astronaut at landing. Fundus examination revealed bilateral, asymmetrical disc edema.
On visual field examination, the physician may elicit an enlarged blind spot; the visual acuity may remain relatively intact until papilledema is severe or prolonged.
In keratoendotheliitis fugax hereditaria, patients suffer from periodical transient inflammation of the corneal endothelium and stroma, leading to short term obscuration of vision and, in some patients after repeated attacks, to central corneal stromal opacities. [4] [5] [6] Approximately 50 known cases have been reported in the literature.
"For some people, it goes beyond the visual cortex," Broner says. "They have stroke-like symptoms where the words aren't coming out right or it sounds garbled," she explains. They might also have ...
Distribution of rods and cones along a line passing through the fovea and the blind spot of a human eye [1]. A blind spot, scotoma, is an obscuration of the visual field.A particular blind spot known as the physiological blind spot, "blind point", or punctum caecum in medical literature, is the place in the visual field that corresponds to the lack of light-detecting photoreceptor cells on the ...
Epigenetic reprogramming through a novel gene therapy shows promise in restoring vision loss in a non-human primate model of NAION. This study builds on previous research demonstrating that AAV2-induced transient expression of the reprogramming genes Oct4, Sox2, and Klf4 (OSK) could reverse retinal aging and restore visual function in mice.