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Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Mild symptoms include abdominal bloating and feeling of fullness, nausea, diarrhea, and slight weight gain. Moderate symptoms include weight gain greater than 1 kg (2.2 lb) per day, increased abdominal girth, vomiting, diarrhea, darker urine, decreased urine output, excessive thirst, and skin and/or hair feeling dry (in addition to mild symptoms).
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This termination of menses is associated with a dramatic drop in estrogen levels. The estrogen levels stated previously dramatically decrease to approximately 20 pg/ml [5] or less when menopause begins. Menopause falls under the umbrella of conditions related to hypoestrogenism. There are many symptoms associated with the transition and ...
Synthetic progestin lacks the ability to antagonize mineralocorticoid receptors, leading to more sodium and water retention and subsequently, temporary weight gain. [15] In addition, estrogen is known to interfere with the renin-angiotensin-aldosterone system (RAAS), since high concentrations of estrogen causes the release of more angiotensin ...
Bob Wood, R.Ph., lists the symptoms of estrogen dominance as "fibrocystic and tender breasts, heavy menstrual bleeding, irregular menstrual cycles, mood swings, vasomotor symptoms, weight gain and uterine fibroids" and believes that testing and "balancing hormones is of benefit to women of all ages". [7]
Researchers looked into hormone levels during the cycles of female mice before giving them alcohol - discovering that female mice drink much more when they have high levels of estrogen than on ...