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The acceptor stem is a 7- to 9-base pair (bp) stem made by the base pairing of the 5′-terminal nucleotide with the 3′-terminal nucleotide (which contains the CCA tail used to attach the amino acid). The acceptor stem may contain non-Watson-Crick base pairs. [6] [8]
RNA splicing is a process in molecular biology where a newly-made ... which is 3' acceptor site, folds into three stem loop structures, i.e. Intronic splicing ...
Most conserved is the primary sequence of the amino acyl acceptor stem. This portion of the molecule has an invariable A residue in the discriminator position and a G-U pair at position 3 (except in S eculamonas ecuadoriensis , which has a G-C pair); this position is the recognition site for alanyl tRNA synthase.
Overview of eukaryotic messenger RNA (mRNA) translation Translation of mRNA and ribosomal protein synthesis Initiation and elongation stages of translation involving RNA nucleobases, the ribosome, transfer RNA, and amino acids The three phases of translation: (1) in initiation, the small ribosomal subunit binds to the RNA strand and the initiator tRNA–amino acid complex binds to the start ...
The third arm, known as the "variable arm", has a stem with optional loop. [2] One end of the chains (with a double stranded structure in which the 5' and 3' ends are adjacent to each other), the amino acids acceptor stem, usually attaches to amino acids and such reactions are often catalyzed by a specific enzymes, aminoacyl tRNA synthetase. [3]
Transfer RNA. The D arm is a feature in the tertiary structure of transfer RNA (tRNA). It is composed of the two D stems and the D loop. The D loop contains the base dihydrouridine, for which the arm is named. [1] The D loop's main function is that of recognition.
Amino acid activation (also known as aminoacylation or tRNA charging) refers to the attachment of an amino acid to its respective transfer RNA (tRNA). The reaction occurs in the cell cytosol and consists of two steps: first, the enzyme aminoacyl tRNA synthetase catalyzes the binding of adenosine triphosphate (ATP) to a corresponding amino acid, forming a reactive aminoacyl adenylate ...
Transfer RNA. The T-arm or T-loop is a specialized region on the tRNA molecule which acts as a special recognition site for the ribosome to form a tRNA-ribosome complex during protein biosynthesis or translation (biology). The T-arm has two components to it; the T-stem and the T-loop.