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The COVID-19 vaccines are widely credited for their role in reducing the severity and death caused by COVID-19. [ 128 ] [ 129 ] As of March 2023, more than 5.5 billion people had received one or more doses [ 130 ] (11.8 billion in total) in over 197 countries.
COVID-19 simulation models are mathematical infectious disease models for the spread of COVID-19. [1] The list should not be confused with COVID-19 apps used mainly for digital contact tracing . Note that some of the applications listed are website-only models or simulators, and some of those rely on (or use) real-time data from other sources.
The terms "intrinsic incubation period" and "extrinsic incubation period" are used in vector-borne diseases.The intrinsic incubation period is the time taken by an organism to complete its development in the definitive host.
Chalk COVID-19 and VE day themed mural in May 2020. COVID-19 pandemic in popular culture; Impact of the COVID-19 pandemic on the arts and cultural heritage; Impact of the COVID-19 pandemic on cinema; Impact of the COVID-19 pandemic on the performing arts; Impact of the COVID-19 pandemic on social media; Impact of the COVID-19 pandemic on sports
The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
Diagram of the genome and functional domains of the S protein for SARS-CoV and MERS-CoV. The spikes are the most distinguishing feature of coronaviruses and are responsible for the corona- or halo-like surface. On average a coronavirus particle has 74 surface spikes. [53] Each spike is about 20 nm long and is composed of a trimer of the S protein.
This article documents the chronology and epidemiology of SARS-CoV-2 in 2019, the virus that causes coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 known to have been identified were in Wuhan , Hubei , China , in December 2019.