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  2. Tetracycline-controlled transcriptional activation - Wikipedia

    en.wikipedia.org/wiki/Tetracycline-controlled...

    The Tet-On Advanced transactivator (also known as rtTA2 S-M2) is an alternative version of Tet-On that shows reduced basal expression, and functions at a 10-fold lower Dox concentration than Tet-Off. In addition, its expression is considered to be more stable in eukaryotic cells due to being human codon optimized and utilizing three minimal ...

  3. TET enzymes - Wikipedia

    en.wikipedia.org/wiki/TET_enzymes

    The TET enzymes are a family of ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation . 5-Methylcytosine (see first Figure) is a methylated form of the DNA base cytosine (C) that often regulates gene transcription and has several other functions in the genome.

  4. Tet methylcytosine dioxygenase 1 - Wikipedia

    en.wikipedia.org/wiki/Tet_methylcytosine_di...

    Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene.Its function, regulation, and utilizable pathways remain a matter of current research while it seems to be involved in DNA demethylation and therefore gene regulation, [5] [6] but is expressed as different isoforms which may have distinct functions.

  5. Active transport - Wikipedia

    en.wikipedia.org/wiki/Active_transport

    Active transport is essential for various physiological processes, such as nutrient uptake, hormone secretion, and nerve impulse transmission. For example, the sodium-potassium pump uses ATP to pump sodium ions out of the cell and potassium ions into the cell, maintaining a concentration gradient essential for cellular function. Active ...

  6. Biomolecular gradient - Wikipedia

    en.wikipedia.org/wiki/Biomolecular_gradient

    The grey represents the concentration of a molecule. A biomolecular gradient is established by a difference in the concentration of molecules in a biological system such as individual cells, groups of cells, or an entire organism. A biomolecular gradient can exist intracellularly (within a cell) or extracellularly (between groups of cells).

  7. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    This exchange leads to a reduced cytoplasmic concentration of tetracycline. [33] In ribosomal protection, a resistance gene encodes a protein that can have several effects, depending on what gene is transferred. [34] Twelve classes of ribosomal protection genes/proteins have been found. [35]

  8. Doxycycline - Wikipedia

    en.wikipedia.org/wiki/Doxycycline

    Doxycycline has a high oral bioavailability, as it is almost completely absorbed in the stomach and proximal small intestine. [15] Unlike other tetracyclines, its absorption is not significantly affected by food or dairy intake. [15] However, co-administration of dairy products reduces the serum concentration of doxycycline by 20%. [15]

  9. TetR - Wikipedia

    en.wikipedia.org/wiki/TetR

    Tet Repressor proteins (otherwise known as TetR) are proteins playing an important role in conferring antibiotic resistance to large categories of bacterial species. Tetracycline (Tc) is a broad family of antibiotics to which bacteria have evolved resistance.