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In some areas, skeletal fluorosis is endemic. While fluorosis is most severe and widespread in the world's two most populous countries – India and China – UNICEF estimates that "fluorosis is endemic in at least 25 countries across the globe. The total number of people affected is not known, but a conservative estimate would number in the ...
Metabolic bone disease is an abnormality of bones caused by a broad spectrum of disorders. Most commonly these disorders are caused by deficiencies of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated.
The use of fluoride supplements during the last six months of pregnancy has no significant impact on the incidence of fluorosis in children. [16] Optimal water fluoridation for the prevention of dental caries increases the prevalence of dental fluorosis by 4 to 5%. [13] The observed effects are mild to moderate, usually of minimal aesthetic ...
Osteitis fibrosa cystica (/ ˌ ɒ s t i ˈ aɪ t ɪ s f aɪ ˈ b r oʊ s ə ˈ s ɪ s t ɪ k ə / OSS-tee-EYE-tis fy-BROH-sə SIS-tik-ə) is a skeletal disorder resulting in a loss of bone mass, a weakening of the bones as their calcified supporting structures are replaced with fibrous tissue (peritrabecular fibrosis), and the formation of cyst-like brown tumors in and around the bone.
Fluorosis becomes possible above this recommended dosage. As of 2015, the United States Health and Human Services Department recommends a maximum of 0.7 milligrams of fluoride per liter of water – updating and replacing the previous recommended range of 0.7 to 1.2 milligrams issued in 1962. The new recommended level is intended to reduce the ...
Researchers say the treatment — deep brain stimulation, or DBS — could eventually help many of the nearly 3 million Americans with depression that resists other treatments. It's approved for ...
Fluorosis may refer to: Dental fluorosis , a disturbance of dental enamel caused by excessive exposure to high concentrations of fluoride during tooth development. Skeletal fluorosis , a bone disease caused by excessive accumulation of fluoride in the bones
Most patients are asymptomatic, with the diagnosis often established after an incidental finding or with pain, swelling, or fracture. Lesions usually enlarge in proportion to skeletal growth and the abnormal replacement remain active only until skeletal maturity. [5] Monostotic fibrous dysplasia does not convert into the polyostotic type.