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Leaves of the coca plant (Erythroxylum novogranatense var. Novogranatense), from which cocaine, a naturally occurring local anesthetic, is derived [1] [2]. An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia — in other words, to result in a temporary loss of sensation or awareness.
Norcocaine is a minor metabolite of cocaine. It is the only confirmed pharmacologically active metabolite of cocaine, [1] although salicylmethylecgonine is also speculated to be an active metabolite. The local anesthetic potential of norcocaine has been shown to be higher than that of cocaine, [2] [3] however cocaine continues to be more widely ...
Cocaine (from French cocaïne, from Spanish coca, ultimately from Quechua kúka) [13] is a tropane alkaloid that acts as a central nervous system stimulant.As an extract, it is mainly used recreationally and often illegally for its euphoric and rewarding effects.
In Europe, North America, and some parts of Asia, the most common form of cocaine is a white crystalline powder. Cocaine is a stimulant but is not normally prescribed therapeutically for its stimulant properties, although it sees clinical use as a local anesthetic, in particular in ophthalmology . [ 152 ]
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
WebMD said this is due to several factors: the types of drugs mixed in the pink cocaine; whether alcohol is involved; how much pink cocaine is taken; and how the body reacts to the drugs.
General anaesthetics (or anesthetics) are often defined as compounds that induce a loss of consciousness in humans or loss of righting reflex in animals. Clinical definitions are also extended to include an induced coma that causes lack of awareness to painful stimuli, sufficient to facilitate surgical applications in clinical and veterinary practice.
A partial autopsy conducted on former One Direction singer Liam Payne found multiple substances in his system when he fell to his death from the third-floor balcony of a hotel room in Argentina ...