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Vortioxetine was under development for the treatment of generalized anxiety disorder [59] and attention-deficit hyperactivity disorder (ADHD) [60] but development for these indications was discontinued. [61] As of August 2021, vortioxetine remains in development for the treatment of anxiety disorders, binge-eating disorder, and bipolar disorder ...
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual) , in the cheek (buccal) , by injection ( intravenous and subcutaneous ), as a skin patch (transdermal) , or as an implant .
Guanfacine is also used off-label to treat tic disorders, anxiety disorders such as generalized anxiety disorder, and PTSD. [ 24 ] [ 15 ] Guanfacine and other α 2A -adrenergic receptor agonists have anxiolytic -like action, [ 25 ] thereby reducing the emotional responses of the amygdala , and strengthening prefrontal cortical regulation of ...
Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.
Stress is highly individualized and depends on variables such as the novelty, rate, intensity, duration, or personal interpretation of the input, and genetic or experiential factors. Both acute and chronic stress can intensify morbidity from anxiety disorders. One person's fun may be another person's stressor.
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