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Laboratory tests for thrombocytopenia might include full blood count, liver enzymes, kidney function, vitamin B 12 levels, folic acid levels, erythrocyte sedimentation rate, and peripheral blood smear.
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel ).
Approximately 10% of newborns affected by ITP will have platelet counts <50,000/uL and 1% to 2% will have a risk of intracerebral hemorrhage, comparable to that of infants with neonatal alloimmune thrombocytopenia (NAIT). [64] [65] No lab test can reliably predict if neonatal thrombocytopenia will occur.
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
Unlike HUS and aHUS, [39] [40] TTP is known to be caused by a defect in the ADAMTS13 protein, [41] so a lab test showing ≤5% of normal ADAMTS13 levels is indicative of TTP. [28] ADAMTS13 levels above 5%, coupled with a positive test for shiga-toxin / enterohemorrhagic E. coli (EHEC), are more likely indicative of HUS, [ 42 ] whereas absence ...
Pseudothrombocytopenia (PTCP) or spurious thrombocytopenia is an in-vitro sampling problem which may mislead the diagnosis towards the more critical condition of thrombocytopenia. The phenomenon may occur when the anticoagulant used while testing the blood sample causes clumping of platelets which mimics a low platelet count. [ 1 ]
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