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In New Zealand, clobazam is marketed as Frisium [16] In the United Kingdom clobazam (Frisium) is approved for short-term (2–4 weeks) relief of acute anxiety in patients who have not responded to other drugs, with or without insomnia and without uncontrolled clinical depression. [8]
Triazolam is usually used for short-term treatment of acute insomnia and circadian rhythm sleep disorders, including jet lag. It is an ideal benzodiazepine for this use because of its fast onset of action and short half-life. It puts a person to sleep for about 1.5 hours, allowing its user to avoid morning drowsiness.
Butabarbital (brand name Butisol) is a prescription barbiturate sleep aid and anxiety medication.Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia, relieving general anxiety and relieving anxiety before surgical procedures; however it is also ...
Prazepam is indicated for the short-term treatment of anxiety. After short-term therapy, the dose is usually gradually tapered-off to reduce or avoid any withdrawal or rebound effects . [ 5 ] [ 6 ] Desmethyldiazepam , an active metabolite , has a very long half-life of 36 to 200 hours, which contributes to the therapeutic effects of prazepam.
Lormetazepam is a short-acting benzodiazepine and is sometimes used in patients who have difficulty in maintaining sleep or falling asleep. Hypnotics should only be used on a short-term basis or, in those with chronic insomnia, on an occasional basis. [7]
Next day drowsiness is common and may increase during the initial phase of treatment as accumulation occurs until steady-state plasma levels are attained. A 2009 meta-analysis found a 44% higher rate of mild infections, such as pharyngitis or sinusitis, in people taking hypnotic drugs compared to those taking a placebo. [6]
Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. [2] [6] Administration is by mouth. [7]
Nitrazepam, sold under the brand name Mogadon among others, [2] [3] is a hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia. [4] It also has sedative (calming) properties, [ 5 ] as well as amnestic (inducing forgetfulness), anticonvulsant , and skeletal muscle relaxant effects.