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Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
Factors that can increase the D LCO include polycythaemia, asthma (can also have normal D LCO) and increased pulmonary blood volume as occurs in exercise.Other factors are left to right intracardiac shunting, mild left heart failure (increased blood volume) and alveolar hemorrhage (increased blood available for which CO does not have to cross a barrier to enter).
Lung volumes and lung capacities are measures of the volume of air in the lungs at different phases of the respiratory cycle. The average total lung capacity of an adult human male is about 6 litres of air. [1] Tidal breathing is normal, resting breathing; the tidal volume is the volume of air that is inhaled or exhaled in only a single such ...
Many of the factors that regulate the heart rate also affect cardiac function by altering the stroke volume. While a number of variables are involved, stroke volume is dependent upon the difference between end diastolic volume and end systolic volume. The three primary factors involved are preload, afterload and contractility. [1]
Diffusing capacity of the lung (D L) (also known as transfer factor) measures the transfer of gas from air in the lung, to the red blood cells in lung blood vessels. It is part of a comprehensive series of pulmonary function tests to determine the overall ability of the lung to transport gas into and out of the blood.
Due to the intrinsic property of myocardium that is responsible for the Frank-Starling mechanism, the heart can automatically accommodate an increase in venous return, at any heart rate. [ 1 ] [ 10 ] The mechanism is of functional importance because it serves to adapt left ventricular output to right ventricular output. [ 3 ]
The actual values in the lung vary depending on the position within the lung. If taken as a whole, the typical value is approximately 0.8. [4] Because the lung is centered vertically around the heart, part of the lung is superior to the heart, and part is inferior. This has a major impact on the V/Q ratio: [5] apex of lung – higher; base of ...
A medical monitoring device displaying a normal human heart rate. Heart rate is the frequency of the heartbeat measured by the number of contractions of the heart per minute (beats per minute, or bpm). The heart rate varies according to the body's physical needs, including the need to absorb oxygen and excrete carbon dioxide.