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Beta-1 adrenergic receptor. The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors. [ 5 ] It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein that is expressed predominantly in cardiac tissue.
1. -adrenergic agonist. β1-Adrenergic receptor agonists, also known as beta-1 agonists, are a class of drugs that bind selectively to the β 1 -adrenergic receptor. As a result, they act more selectively upon the heart. β-Adrenoceptors typically bind to norepinephrine release by sympathetic adrenergic nerves and to circulating epinephrine.
Beta blocker. Skeletal formula of propranolol, the first clinically successful beta blocker. Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms (arrhythmia), and to protect the heart from a second heart attack after a first heart attack (secondary prevention). [1]
Bisoprolol. Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [ 7 ] and used for cardiovascular diseases, [ 7 ] including tachyarrhythmias, high blood pressure, angina, and heart failure. [ 7 ][ 8 ] It is taken by mouth. [ 7 ]
Dobutamine is a direct-acting agent whose primary activity results from stimulation of the β 1-adrenoceptors of the heart, increasing contractility and cardiac output. Since it does not act on dopamine receptors to inhibit the release of norepinephrine (another α 1 agonist), dobutamine is less prone to induce hypertension than is dopamine.
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α 1, α 2, β 1, β 2, and β 3, although there are more subtypes, and agonists vary in specificity between these receptors, and may be classified respectively. However, there are also other mechanisms ...
Beta-adrenergic agonist. Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing. [1] They are a class of sympathomimetic agents, each acting upon the beta adrenoceptors. [2] In general, pure beta-adrenergic agonists have the opposite function ...
Propranolol is a medication of the beta blocker class. [2] It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, [2] [3] [4] as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. [2]