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D-Phenylalanine (DPA, D-Phe), sold under the brand names Deprenon, Sabiben, and Sabiden, is an enantiomer of phenylalanine which is described as an antidepressant and is marketed as a prescription drug for medical use in Argentina. [1] [2] The medication has been marketed since at least the 1970s [3] and continued to be available by the 2000s. [1]
D-Phenylalanine is a psychostimulant and selective norepinephrine releasing agent (NRA) or norepinephrine-preferring norepinephrine–dopamine releasing agent (NDRA). [ 1 ] [ 2 ] The EC 50 Tooltip half-maximal effective concentration values of D -phenylalanine for monoamine release are 106 nM for norepinephrine, 1,355 nM for dopamine , and ...
D-Phenylalanine (DPA, D-Phe; Deprenon, Sabiben, Sabiden) – enkephalinase inhibitor; Agomelatine (Valdoxan) – 5-HT 2C receptor antagonist and MT 1 and MT 2 receptor agonist; Brexanolone (allopregnanolone; Zulresso) – GABA A receptor positive allosteric modulator – approved for postpartum depression
Diphenylalanine is a term that has recently been used to describe the unnatural amino acid similar to the two amino acids alanine and phenylalanine. It has been used for the synthesis of pseudopeptide analogues which are capable of inhibiting certain enzymes. [1]
Miindfulness-based stress reduction may be as effective as escitalopram (Lexapro — an SSRI commonly used to treat depression and anxiety), in relieving anxiety symptoms, a new study has found.
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