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The most common side effects associated with methylphenidate (in standard and extended-release formulations) are appetite loss, dry mouth, anxiety/nervousness, nausea, and insomnia. [82] Gastrointestinal adverse effects may include abdominal pain and weight loss .
The oral bioavailability of amphetamine varies with gastrointestinal pH; [29] it is well absorbed from the gut, and bioavailability is typically 90%. [10] Amphetamine is a weak base with a p K a of 9.9; [ 3 ] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich ...
Methamphetamine [note 1] (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational or performance-enhancing drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder (ADHD). [24]
Dry spells are not uncommon and may occur at any time of the year. Extremes do occur, such as the 114 mm (4.49 in) of rainfall that fell on July 31, 1953. [ 85 ] Much of the precipitation that Edmonton receives in the summer comes from late-day thunderstorms, [ 96 ] [ 97 ] which are frequent and occasionally severe enough to produce large hail ...
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