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The EMA also initiated an assessment for all COVID‑19 vaccines used in the EU for immune thrombocytopenia (ITP), described as low blood platelet levels that could lead to bruising and bleeding, as a possible side effect, whilst also stating that up to this point no link with any COVID‑19 had been established. [12]
Health Canada received a submission from Moderna on June 29, 2023, for yet another reformulated COVID-19 vaccine based on the Omicron XBB.1.5 subvariant of SARS-CoV-2. [131] The updated version was tested in a small human trial of 101 participants who had previously received four doses of previous formulations of the Moderna COVID-19 vaccine.
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 vaccines. These characteristics include efficacy , effectiveness , and safety. As of November 2022 [update] , 40 vaccines are authorized by at least one national regulatory authority for public use: [ 1 ] [ 2 ]
The findings in the new report come from the analysis of nearly 1,300 death certificates of Oregon residents ages 16 to 30 who died from any heart condition or unknown reasons between June 1, 2021 ...
The vaccine consists of a version of the receptor binding domain (RBD) of the SARS‑CoV‑2 spike protein, together with the adjuvants aluminium hydroxide gel and CpG 1018. [2] As the RBD protein is poorly immunogenic alone, adjuvantation is essential for a RBD-based vaccine immunogenicity. [ 9 ]
PTX-COVID19-B is a messenger RNA (mRNA)-based COVID-19 vaccine, a vaccine for the prevention of the COVID-19 disease caused by an infection of the SARS-CoV-2 coronavirus, created by Providence Therapeutics—a private Canadian drug company co-founded by Calgary, Alberta-based businessman Brad T. Sorenson and San Francisco–based Eric Marcusson ...
When the Oxford–AstraZeneca COVID-19 vaccine's age limit was lowered in late April, many eligible Canadians from Generation X [15] quickly used up the vaccine supply as it was not being used by the previous group limited to 55 years of age and older. [17] Vaccine Hunters spent considerable time working on high public interest for the vaccine ...
Users of this vaccine passport, the first in Canada, faced fewer COVID-19 public health restrictions. [2] By early July, the demand for the paper vaccine passports temporarily overwhelmed the system. At the same time, the province reached a new "marker in the pandemic"—the COVID-19 vaccines supply exceeded "demand on a daily basis." [2] [44]