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A microfibril is a very fine fibril, or fiber-like strand, consisting of glycoproteins and cellulose.It is usually, but not always, used as a general term in describing the structure of protein fiber, e.g. hair and sperm tail.
Fibrillin-1 is a major component of the microfibrils that form a sheath surrounding the amorphous elastin.It is believed that the microfibrils are composed of end-to-end polymers of fibrillin.
Cellulose chains are observed to align in overlapping parallel arrays, with the similar polarity forming a cellulose microfibril. In plants, these cellulose microfibrils arrange themselves into layers, formally known as lamellae, and are stabilized in the cell wall by surface, long cross-linking glycan molecules. Glycan molecules increase the ...
Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene. [5] [6]Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases.
MFAP4 (microfibril-associated glycoprotein 4) is an extracellular matrix protein encoded by the MFAP4 gene. It is part of the MFAP family of proteoglycans , which are involved in cell adhesion, intercellular interactions and the assembly and/or maintenance of elastic fibres .
It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs.
11117 100952 Ensembl ENSG00000138080 ENSMUSG00000029163 UniProt Q9Y6C2 Q99K41 RefSeq (mRNA) NM_007046 NM_133918 RefSeq (protein) NP_008977 NP_598679 Location (UCSC) Chr 2: 27.08 – 27.09 Mb Chr 5: 31.07 – 31.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse For other uses, see Emilin. Elastin microfibril interfacer 1 (EMILIN-1) is a protein that in humans is encoded by the ...
2200 14118 Ensembl ENSG00000166147 ENSMUSG00000027204 UniProt P35555 Q61554 RefSeq (mRNA) NM_000138 NM_007993 RefSeq (protein) NP_000129 NP_032019 Location (UCSC) Chr 15: 48.41 – 48.65 Mb Chr 2: 125.14 – 125.35 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibrillin-1 is a protein that in humans is encoded by the FBN1 gene, located on chromosome 15. It is a large, extracellular ...