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Only the Wolff–Chaikoff effect is helpful to prevent the thyroid from uptaking radioactive iodine in the case of nuclear emergencies. Therefore, "plummering" with high-dose iodine is only effective in a short time window after the release of radionuclides. [15] Wrong timing of iodine use may even increase the risk by triggering the Plummer ...
Iodine deficiency is the most common cause of primary hypothyroidism and endemic goiter worldwide. [8] [9] In areas of the world with sufficient dietary iodine, hypothyroidism is most commonly caused by the autoimmune disease Hashimoto's thyroiditis (chronic autoimmune thyroiditis). [8] [9] Hashimoto's may be associated with a goiter.
Though the exact cause of myxedema is still unclear, a wealth of research has demonstrated the importance of iodine. [10] In an important study [11] the researchers showed that in the myxedematous type of cretinism treatment with iodine normalizes thyroid function provided that the treatment is begun early in the postnatal period. If not, the ...
Iodine deficiency is the most common cause of hypothyroidism worldwide, [53] and the autoimmune disease Hashimoto's thyroiditis is the most common cause in the developed world. [54] Other causes include congenital abnormalities, diseases causing transient inflammation, surgical removal or radioablation of the thyroid, the drugs amiodarone and ...
It is the most common cause of hypothyroidism in areas of sufficient iodine. [10] Also, the rate of lymphocytic infiltration increased in areas where the iodine intake was once low, but increased due to iodine supplementation. [27] [120] Iodine deficiency disorder is combated using an increase in iodine in a person's diet. When a dramatic ...
Radioiodine therapy with iodine-131 can be used to shrink the thyroid gland (for instance, in the case of large goiters that cause symptoms but do not harbor cancer—after evaluation and biopsy of suspicious nodules has been done), or to destroy hyperactive thyroid cells (for example, in cases of thyroid cancer). The iodine uptake can be high ...