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E-nose showed the ability to smell the cause of the exacerbation. [8] The definition of a COPD exacerbation is commonly described as "lost in translation", [9] meaning that there is no universally accepted standard with regard to defining an acute exacerbation of COPD. Many organizations consider it a priority to create such a standard, as it ...
For exacerbations that result in a visit to the Emergency Department (ED), oral methylprednisolone is preferred over intravenous administration, unless there are issues with adherence or vomiting. [ 15 ] [ 16 ] Oral methylprednisolone is less invasive and studies have shown that equivalent efficacy compared to intravenous methylprednisolone.
Used in acute exacerbation; 5–7 days of treatment is considered; Risk of exacerbation can be lessen by regular use of macrolides; Only be used when the patient experience three cardinal symptoms of COPD exacerbation: worsening dyspnea, increasing sputum production and purulence [28] Caution [44] [47] Change to other type if allergic to ...
Prednisolone is a synthetic pregnane corticosteroid closely related to its cognate prednisone, having identical structure save for two fewer hydrogens near C 11. It is also known as δ 1 -cortisol , δ 1 -hydrocortisone , 1,2-dehydrocortisol , or 1,2-dehydrohydrocortisone , as well as 11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione .
If high doses were used for six to 10 days, reduce to replacement dose immediately and taper over four more days. Adrenal recovery can be assumed to occur within two to four weeks of completion of steroids. If high doses were used for 11–30 days, cut immediately to twice replacement, and then by 25% every four days.
This page was last edited on 30 April 2009, at 01:48 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
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