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The roentgen equivalent man (rem) [1] [2] is a CGS unit of equivalent dose, effective dose, and committed dose, which are dose measures used to estimate potential health effects of low levels of ionizing radiation on the human body.
A radioligand is a microscopic particle which consists of a therapeutic radioactive isotope and the cell-targeting compound - the ligand. The ligand is the target binding site, it may be on the surface of the targeted cancer cell for therapeutic purposes. Radioisotopes can occur naturally or be synthesized and produced in a cyclotron/nuclear ...
Roentgen a legacy unit of measurement for the exposure of X-rays; Each measure is often simply described as ‘dose’, which can lead to confusion. Non-SI units are still used, particularly in the USA, where dose is often reported in rads and dose equivalent in rems. By definition, 1 Gy = 100 rad and 1 Sv = 100 rem.
A third technique is to enhance the radiosensitivity of the cancer by giving certain drugs during a course of radiation therapy. Examples of radiosensitizing drugs include cisplatin, nimorazole, and cetuximab. [11] The impact of radiotherapy varies between different types of cancer and different groups. [12]
Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. [1] It is a form of unsealed source radiotherapy. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to ...
This included a proposal to discontinue use of equivalent dose as a separate protection quantity. This would avoid confusion between equivalent dose, effective dose and dose equivalent, and to use absorbed dose in Gy as a more appropriate quantity for limiting deterministic effects to the eye lens, skin, hands & feet. [10]
This concept is described as a binary system using two separate components for the therapy of cancer. Each component in itself is relatively harmless to the cells, but when combined for treatment they produce a highly cytocidal effect which is lethal (within a limited range of 5-9 micrometers or approximately one cell diameter). Clinical trials ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...