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Porphyria / p ɔːr ˈ f ɪr i ə / is a group of disorders in which substances called porphyrins build up in the body, adversely affecting the skin or nervous system. [1] The types that affect the nervous system are also known as acute porphyria, as symptoms are rapid in onset and short in duration. [1]
There are no pathognomonic signs or symptoms. [citation needed] The most common identified triggers for acute attacks are medications, weight loss diets, and surgery. [14] Many medications have been associated with AIP including antibiotics, hormonal contraceptives, seizure medications, anesthetics, and HIV treatment drugs. [15]
The disease can present during early childhood (as well as in adulthood) with acute neurologic symptoms that resemble those encountered in acute intermittent porphyria. [1] Patients can also have gastrointestinal symptoms during acute attacks, including abdominal cramping, vomiting, and constipation. [2]
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Variegate porphyria, also known by several other names, is an autosomal dominant porphyria [3] that can have acute (severe but usually not long-lasting) symptoms along with symptoms that affect the skin. The disorder results from low levels of the enzyme responsible for the seventh step in heme production.
“THE MOST OBVIOUS signs of male anxiety are the physical ones,” says Lindsay Israel, M.D., psychiatrist and chief medical officer at Success TMS. “Men might find themselves going to the ...
Erythropoietic protoporphyria (or commonly called EPP) is a form of porphyria, which varies in severity and can be very painful.It arises from a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the red blood cells (erythrocytes), plasma, skin, and liver. [2]
Pelvic Floor Dysfunction in Men: Causes, Symptoms, and Treatment This article was reviewed by Martin Miner, MD. Although we don’t pay much attention to our pelvic floor muscles, they make ...
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