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Porphyria / p ɔːr ˈ f ɪr i ə / is a group of disorders in which substances called porphyrins build up in the body, adversely affecting the skin or nervous system. [1] The types that affect the nervous system are also known as acute porphyria, as symptoms are rapid in onset and short in duration. [1]
The disease can present during early childhood (as well as in adulthood) with acute neurologic symptoms that resemble those encountered in acute intermittent porphyria. [1] Patients can also have gastrointestinal symptoms during acute attacks, including abdominal cramping, vomiting, and constipation. [2]
Variegate porphyria, also known by several other names, is an autosomal dominant porphyria [3] that can have acute (severe but usually not long-lasting) symptoms along with symptoms that affect the skin. The disorder results from low levels of the enzyme responsible for the seventh step in heme production.
The dog then causes further trauma to the skin by itching and rubbing at the area, leading to a secondary bacterial infection." Acute moist dermatitis: Symptoms A patch of moist, inflamed skin ...
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Signs include vomiting, diarrhea, abdominal pain, lethargy, and anorexia. [146] Inflammatory bowel disease (IBD)* is a group of diseases in dogs that are idiopathic and characterized by the presence of inflammatory cell infiltrates in the stomach and/or intestinal walls. It is a common condition. Signs include vomiting, diarrhea, and weight loss.
Here are some common signs of frostbite in dogs: Discoloration of an area – usually pale with a bluish tinge. This sign is most noticeable in areas such as the ears, paws, tail, and nose.
Erythropoietic protoporphyria (or commonly called EPP) is a form of porphyria, which varies in severity and can be very painful.It arises from a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the red blood cells (erythrocytes), plasma, skin, and liver. [2]