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Spindle cell sarcoma is a type of connective tissue cancer. The tumors generally begin in layers of connective tissue, as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size. At first, the lump is, small in size, as the tumor exists in stage 1, and will not ...
Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men. [ 1 ] : 625 [ 2 ] Signs and symptoms
In neurobiology, spindle cell refers to: Spindle neuron, also known as a von Economo neuron; In general medicine, a spindle cell may refer to the spindle-shaped cells that are found in certain types of tumor: Inflammatory fibroid polyp; Pigmented spindle cell nevus; Spindle cell carcinoma; Spindle cell lipoma; Spindle cell sarcoma
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma .
Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men and are characterized by floret giant cells with overlapping nuclei. [7]: 625 Spindle-cell lipomas are asymptomatic, slow-growing, subcutaneous tumors that have a predilection for the posterior back, neck, and shoulders of older men.
The most typical feature of Kaposi sarcoma is the presence of spindle cells forming slits containing red blood cells. Mitotic activity is only moderate and pleomorphism is usually absent. [ 31 ] The tumor is highly vascular , containing abnormally dense and irregular blood vessels, which leak red blood cells into the surrounding tissue and give ...
Microscopic histopathologic views of hematoxylin and eosin stained tumor tissue show whorled and bundled, uniform, bland-appearing, slender fibroblastic spindle-shaped cells with elongated, tapered nuclei. The cells have scant cytoplasm and do not appear to be rapidly proliferating as defined by their low rate of mitosis.
The UPS subtype of these sarcomas consists of tumor cells that are poorly differentiated and may appear as spindle-shaped cells, histiocytes, and giant cells. [7] UPS is considered a diagnosis that defies formal sub-classification after thorough histologic , immunohistochemical , and ultrastructural examinations fail to identify the type of ...
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