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Hoofnagle leads the Liver Disease Research Branch at NIDDK, [4] and has done so since he was tapped for the position in 2003. [5] In this capacity, Hoofnagle oversees the Drug-Induced Liver Injury Network and LiverTox, a database that provides "comprehensive and unbiased information about drug induced liver injury caused by prescription and nonprescription drugs, herbal and dietary supplements."
Tolfenamic acid finds utility in the prevention and treatment of conditions associated with pain and inflammation. [8] [9] However, despite its efficacy when administered intramuscularly, subcutaneously, or orally, [10] TFA-based drugs have not yet gained approval in the United States and some other countries due to the significant number of reported side effects.
CRISP was a fully searchable database of biomedical research projects funded by the U.S. government. It covers projects going back to 1972 and records name and abstract of the project, the principal investigator and the involved institution. The database is maintained by the Office of Extramural Research at the National Institutes of Health.
The Entrez Global Query Cross-Database Search System is used at NCBI for all the major databases such as Nucleotide and Protein Sequences, Protein Structures, PubMed, Taxonomy, Complete Genomes, OMIM, and several others. [9] Entrez is both an indexing and retrieval system having data from various sources for biomedical research.
Meclofenamic acid (used as meclofenamate sodium, brand name Meclomen) is a drug used for joint, muscular pain, arthritis and dysmenorrhea. [1] It is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs) and was approved by the US FDA in 1980. [2]
National Center for Biotechnology Information is an intramural division within National Library of Medicine that creates public databases in molecular biology, conducts research in computational biology, develops software tools for analyzing molecular and genomic data, and disseminates biomedical information, all for the better understanding of ...
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care.
The National Institutes of Health maintains the LiverTox Archived 2019-07-24 at the Wayback Machine database for consumers to track all known prescription and non-prescription compounds associated with liver injury. [42] Exposure to other hepatotoxins can occur accidentally or intentionally through ingestion, inhalation, and skin absorption.