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  2. Schild equation - Wikipedia

    en.wikipedia.org/wiki/Schild_equation

    The dose ratio r is the ratio of the dose of agonist required for half maximal response with the antagonist present divided by the agonist required for half maximal response without antagonist ("control"). In other words, the ratio of the EC50s of the inhibited and un-inhibited curves. Thus, r represents both the strength of an antagonist and ...

  3. Hemorrhagic gastroenteritis - Wikipedia

    en.wikipedia.org/wiki/Hemorrhagic_gastroenteritis

    Hemorrhagic gastroenteritis (HGE) is a disease of dogs characterized by sudden vomiting and bloody diarrhea. The symptoms are usually severe, and HGE can be fatal if not treated. HGE is most common in young adult dogs of any breed, but especially small dogs such as the Toy Poodle and Miniature Schnauzer. [1] It is not contagious.

  4. Oral rehydration therapy - Wikipedia

    en.wikipedia.org/wiki/Oral_rehydration_therapy

    Oral rehydration therapy (ORT) is a type of fluid replacement used to prevent and treat dehydration, especially due to diarrhea. [1] It involves drinking water with modest amounts of sugar and salts, specifically sodium and potassium. [1]

  5. Clozapine - Wikipedia

    en.wikipedia.org/wiki/Clozapine

    Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. [6] It is primarily used to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.

  6. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Celexa – an antidepressant of the SSRI class; Centrax – an anti-anxiety agent; Clozaril – atypical antipsychotic used to treat resistant schizophrenia; Concerta (methylphenidate) – an extended release form of methylphenidate

  7. Clozapine N-oxide - Wikipedia

    en.wikipedia.org/wiki/Clozapine_N-oxide

    Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), [1] despite the initial belief that it was biologically inert.

  8. Management of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Management_of_schizophrenia

    [149] [150] Clozapine is of benefit to around half of this group although it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in less than 4% of people. [151] [152] [153] Between 12 and 20 per cent will not respond to clozapine and this group is said to have ultra treatment resistant schizophrenia.

  9. Antipsychotic switching - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic_switching

    In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...