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Bovine β-casomorphin 7, a casomorphin, has seven amino acids in its peptide sequence. Casomorphin is an opioid peptide (protein fragment) derived from the digestion of the milk protein casein . [ 1 ]
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a peptide encoded in mitochondrial DNA. It is believed to be involved in skeletal muscle and glucose metabolism. It is upregulated in response to exercise, and is considered an exercise mimetic. [1] [2] MOTS-c binds to casein kinase 2. [3]
Structural correlation between met-enkephalin, an opioid peptide (left), and morphine, an opiate drug (right) Opioid peptides or opiate peptides are peptides that bind to opioid receptors in the brain; opiates and opioids mimic the effect of these peptides. Such peptides may be produced by the body itself, for example endorphins. The effects of ...
Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects.It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cell cytokines. [1]
Casein is the primary emulsifier in milk, that is, it helps in mixing oils, fats, and water in milk. [3] Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive. [4] The most common form of casein is sodium caseinate (historically called nutrose), which is a very efficient emulsifier.
Reichelt hypothesized that long term exposure to these opiate peptides may have effects on brain maturation and contribute to social awkwardness and isolation. On this basis, Reichelt and others have proposed a gluten-free casein-free (GFCF) diet for those with autism to minimize the buildup of opiate peptides. [2]