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Naloxegol (INN; PEGylated naloxol; [4] trade names Movantik and Moventig) is a peripherally acting μ-opioid receptor antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation. [5] It was approved in 2014 in adult patients with chronic, non-cancer pain. [6]
A 2022 study found that two kiwi fruit a day was as effective as psyllium, found in many over-the-counter laxatives, in treating constipation. Foods to avoid when constipated
Many people will turn to laxatives as the first line of defense. While there are many effective over-the-counter products to treat constipation, they can have negative (and often messy—yikes ...
Laxatives are usually over-the-counter medications designed to help those dealing with constipation and having trouble with bowel movements. Usually, laxatives are a consideration after lifestyle ...
Bulk-forming laxatives, also known as roughage, are substances, such as fiber in food and hydrophilic agents in over-the-counter drugs, that add bulk and water to stools so they can pass more easily through the intestines (lower part of the digestive tract). [2] Properties. Site of action: small and large intestines; Onset of action: 12–72 hours
Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals.
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