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A diagram of C. tetani showing the bacterium alone, with a spore being produced, and the spore alone. Clostridium tetani is a rod-shaped, Gram-positive bacterium, typically up to 0.5 μm wide and 2.5 μm long. [1] It is motile by way of various flagella that surround its body. [1] C. tetani cannot grow in the presence of oxygen. [1]
Anti-tetanus immunoglobulin, also known as tetanus immune globulin (TIG) and tetanus antitoxin, is a medication made up of antibodies against the tetanus toxin. [1] It is used to prevent tetanus in those who have a wound that is at high risk, have not been fully vaccinated with tetanus toxoid, or have HIV/AIDS.
Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani [1] in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, tentoxilysin, tetanospasmin, or tetanus neurotoxin.
Tetanus (from Ancient Greek τέτανος 'tension, stretched, rigid'), also known as lockjaw, is a bacterial infection caused by Clostridium tetani and characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts for a few minutes.
A clostridial vaccine is a vaccine for sheep and cattle that protects against diseases caused by toxins produced by an infection with one or more Clostridium bacteria. [1] Clostridial vaccines are often administered to pregnant ewes a few weeks before they are due to give birth, in order to give passive immunity to their lambs. [1]
These treatments are personalized and highly expensive, but they're also highly effective. "Using stem cells from patients with heart failure caused by chemo, we are actively developing new drugs ...
Clostridium tetani toxin, via inhibition of glycine-mediated and GABA-ergic neurotransmission, may lead to tetany. [verification needed] An excess of potassium in grass hay or pasture can trigger winter tetany, or grass tetany, in ruminants. [verification needed] Osteomalacia and rickets due to deficiency of vitamin D [verification needed]
“It can cause severe short-lived symptoms, but typically resolves quickly without treatment,” says Pratima Dibba, MD, a board-certified gastroenterologist practicing in New York City.