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Catharanthus roseus, commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, [2] is a perennial species of flowering plant in the family Apocynaceae.
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
Bioprospecting (also known as biodiversity prospecting) is the exploration of natural sources for small molecules, macromolecules and biochemical and genetic information that could be developed into commercially valuable products for the agricultural, [2] [3] aquaculture, [4] [5] bioremediation, [4] [6] cosmetics, [7] [8] nanotechnology, [4] [9] or pharmaceutical [2] [10] industries.
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There are eight known species. Seven are endemic to Madagascar, [4] though one, C. roseus, is widely naturalized around the world. [2] [5] The eighth species, C. pusillus, is native to India and Sri Lanka. [6] The name Catharanthus comes from the Greek for "pure flower". [7] These are perennial herbs with oppositely or almost oppositely ...
The diverse flora of Madagascar holds potential for natural product research and drug production on an industrial scale; the Madagascar periwinkle (Cataranthus roseus), a source of alkaloids used in the treatment of different cancers, is a famous example. [62]
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