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Colchicine is a medication used to prevent and treat gout, [3] [4] to treat familial Mediterranean fever [5] and Behçet's disease, [6] and to reduce the risk of myocardial infarction. [7] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout.
Colchicine is an alternative for those unable to tolerate NSAIDs. [20] At high doses, side effects (primarily gastrointestinal upset) limit its usage. [98] At lower doses, which are still effective, it is well tolerated. [39] [99] [96] [97] Colchicine may interact with other commonly prescribed drugs, such as atorvastatin and erythromycin ...
Plants in this genus contain toxic amounts of the alkaloid colchicine which is used pharmaceutically to treat gout and Familial Mediterranean fever. [13] The use of the roots and seeds in traditional medicine is thought to have arisen due to the presence of this drug. [14] Its leaves, corm and seeds are poisonous.
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The APG III system, of 2009 (unchanged from the APG systems, of 1998 and 2003), recognizes this family and places it in the order Liliales, in the clade monocots. [1] It is a group of herbaceous perennials with rhizomes or corms.
Colchicum luteum, the yellow colchicum, is a species of flowering plant in the family Colchicaceae, native to Central Asia, Afghanistan, Pakistan, the western Himalayas, and Tibet.
Colchicine is known to cause alopecia. One case report described a patient who accidentally ate the tubers and then experienced hair loss over her entire body, including complete baldness . [ 12 ] Poisonings can occur when the tubers are mistaken for sweet potatoes [ 11 ] or yams and eaten. [ 12 ]