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Postcholecystectomy syndrome (PCS) describes the presence of abdominal symptoms after a cholecystectomy (gallbladder removal). Symptoms occur in about 5 to 40 percent of patients who undergo cholecystectomy, [1] and can be transient, persistent or lifelong. [2] [3] The chronic condition is diagnosed in approximately 10% of postcholecystectomy ...
Biliary sludge has been associated with pregnancy, rapid weight loss, total parenteral nutrition, drugs such as ceftriaxone and octreotide, solid organ transplantation, and gastric surgery. [1] [2] In many of these conditions, it is thought that the impairment in the contractility of the gallbladder leads to the formation of the sludge. [2]
[2] [3] Ceftriaxone has been frequently associated with biliary sludge or biliary pseudolithiasis in subsequent reports. [3] Ceftriaxone is excreted primarily through the urine , but also through the bile, up to 40% of its excretion, with concentrations in the bile 20-150 times higher than in the serum.
In people unable to have surgery, gallbladder drainage may be tried. [5] About 10–15% of adults in the developed world have gallstones. [5] Women more commonly have stones than men and they occur more commonly after age 40. [4] Certain ethnic groups are more often affected; for example, 48% of American Indians have gallstones. [4]
The presence of gallstones, usually visualized by ultrasound, generally necessitates a surgical treatment (removal of the gall bladder, typically via laparoscopy). [ 27 ] Removal of the gallbladder with surgery, known as a cholecystectomy , is the definitive surgical treatment for biliary colic.
Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...
It shows a gallbladder wall that is almost pathologically thickened, at 3 mm. However, there is no apparent edema in the pericholecystic fat. The gallbladder contains biliary sludge, as well as gallstones, which create acoustic shadowing. There is thus gallstones without current cholecystitis.
Patients with cholelithiasis typically present with pain in the right-upper quadrant of the abdomen with the associated symptoms of nausea and vomiting, especially after a fatty meal. The physician can confirm the diagnosis of cholelithiasis with an abdominal ultrasound that shows the ultrasonic shadows of the stones in the gallbladder.