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Goodpasture syndrome (GPS), also known as anti–glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs, glomerulonephritis, [1] and kidney failure. [2]
L-α-Glycerophosphorylcholine (alpha-GPC, choline alfoscerate, sn-glycero-3-phosphocholine) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor [ 1 ] which has been investigated for its potential for the treatment of Alzheimer's disease [ 2 ] and other dementias .
Pulmonary-renal syndrome (PRS) is a rare medical syndrome in which respiratory failure involving bleeding in the lungs and kidney failure (glomerulonephritis) occur. [1] PRS is associated with a high rate of morbidity and death. [1] The term was first used by Goodpasture in 1919 to describe the association of respiratory and kidney failure. [1]
The cause of diffuse proliferative glomerulonephritis (DPGN) depends on the severity of the disease. DPGN is a secondary disease, in that a disease that a patient already has causes DPGN to occur. The most common associated disease of DPGN is severe systemic lupus erythematosus(SLE). [4] Specifically, Lupus nephritis class IV. [5]
Giant papillary conjunctivitis, a disease of the eye; Gigaparsec (Gpc), a unit of distance; Global Plant Clinic, an agricultural organization; Glycophorin C, a sialoglycoprotein; Glycerophosphorylcholine, or alpha-GPC; Glypican, a proteoglycan; GPC Biotech, a German biopharmaceutical company
2719 14734 Ensembl ENSG00000147257 ENSMUSG00000055653 UniProt P51654 Q8CFZ4 RefSeq (mRNA) NM_004484 NM_001164617 NM_001164618 NM_001164619 NM_016697 RefSeq (protein) NP_001158089 NP_001158090 NP_001158091 NP_004475 NP_004475.1 NP_057906 Location (UCSC) Chr X: 133.54 – 133.99 Mb Chr X: 51.36 – 51.7 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glypican-3 is a protein that, in ...
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